Curves+

 
 

  1. Bullet Treat nucleic acids with up to four strands

  2. Bullet Deal with chemically modified bases or backbones

  3. Bullet Deal with minicircles

  4. Bullet Calculate a global helical axis (straight or curvilinear)

  5. Bullet Analyse groove widths and depths

  6. Bullet Analyse backbone dihedrals and sugar puckers

  7. Bullet Calculate bp-axis, intra-bp and inter-bp parameters

  8. Bullet Directly analyse molecular dynamics trajectories

What Curves+ can do ....

Curves+ is a complete rewrite of the Curves approach for analysing the structure of nucleic acids. It respects the international conventions for nucleic acid analysis, runs much faster and provides new data, notably on groove geometries. It also avoids confusion created in earlier studies between so-called "local" and "global" parameters.